[Purpose] The purpose of this study was to confirm the effects of the order of single and multi-joint resistance exercise on body composition, basic physical fitness, isokinetic knee function, and maximal strength in male college students. [Method] For this study, thirty male university students were randomly assigned to 3 groups; a control group (CG, n=10), a single-multi joint exercise group (SMG, n=10), or a multi-single joint exercise group (MSG, n=10). Participants in the exercise groups performed resistance training for three times a week for eight weeks. Two-way repeated measures ANOVA was performed to confirm statistically significant differences. [Result] The results of the study showed that percent body fat(p=.001) significantly decreased in SMG compare to CG, and knee isokinetic muscle function significantly increased in SMG and MSG compare to CG, but no significant difference was found in the post-hoc test. Grip strength(p=.001) was significantly increased in SMG compare to SMG, CG. Back strength(p=.001), sit-up(p=.001) and 1RM(p=.001) were significantly increased in SMG and MSG compare to CG. Sprint(p=.009) was significantly improved in MSG compared to the other groups. [Conclusion] According to our findings, isokinetic muscle function and maximal strength increased regardless of exercise order. Single-multi joint exercises proved effective in reducing percent body fat, while multi-single joint exercises demonstrated improvements in sprint ability.